The number of metastatic colonies 10 days after the intravenous transplantation of EMT6/EF-Luc/EV and EMT6/EF-Luc/UCHL1 cells also revealed that LDN57444 had an antimetastatic effect on UCHL1-expressing cancer cells (Fig. 7f,g). This evidence concerns the gene UCHL1 and cancer.