VEGFA and retinopathy of prematurity: Even though the combination treatment of laser and IVB has 100% success rate in ROP regression in this series of patients, it also should be reserved only for APROP or some severe posterior ROPs, because most of ROPs can be successfully treated with IVB alone or laser monotherapy, and there is potential risk in that blood retinal barrier might be affected by laser [28] and anti-VEGF might leak into the systemic circulation more than the IVB monotherapy, which could increase systemic effect and reduce local effect of anti-VEGF.