Mice were inoculated with 2×106 5T33 tumor cells iv, received 500 cGy WBI 7 days after tumor cell inoculation, and were treated with checkpoint blocking antibodies (200 ug of each antibody ip) at the time points indicated in Figure 3A. Administration of anti-PD-L1 alone eliminated myeloma in ~40% of mice (Figure 2B-E), which is consistent with our previous results [39]. Here, CD274 is linked to neoplasm.