The ‘GastroGenus Gastric Cancer Classifier' is an example of a genomic test panel that adds value beyond histopathology of formalin-fixed cancer tissue by evaluating EBV status, MLH1 promoter methylation and multiple cancer gene sequences to interpret molecular class and to identify actionable mutations revealing clinical trial options or off-label use of an existing drug for metastatic cancer patients who fail standard therapy. This evidence concerns the gene MLH1 and gastric cancer.