Among the anomalies of Mysm1−/− mice, especially defects in the bone marrow (BM) – resulting in lymphopenia, anemia, and thrombocytosis – and in lymphocytes have been described.31, 32 However, no conclusive data are available so far on the function of Mysm1 in the thymus or in other tissues. The gene discussed is MYSM1; the disease is thrombocytosis disease.