Upon univariate analysis the type of underlying carcinoma (tumor type), the type of resection, preoperative chemotherapy (CTx), preoperative gamma-glutamyltransferase (GGT), preoperative aspartate aminotransferase (AST), postoperative GGT, pringle/ischemia time in minutes and postoperative TPO increase predicted postoperative LD with a P-value < 0.1 and were therefore included in multivariate analysis. This evidence concerns the gene TPO and carcinoma.