For example, Fig. 3 (A) shows ovarian cancer module 22, in which the TF EGR1 positively regulates several genes (AEBP1, COL1A1, COL5A1, COL5A3, COL6A1, ITGA5, LOXL2, MMP11, MMP2 and THBS2) and miRNAs (miR-214 and miR-152). Here, MMP2 is linked to ovarian cancer.