To further confirm whether the tumor suppressive effects of miR-34c was directly mediated by MET in NPC, CNE-2 and SUNE-1 cells were co-transfected with miRNA mimic (miR-34c mimic or miR-ctrl) and either the empty pReceiver-M02 vector control (Vector) or pReceiver-M02-MET plasmid (MET), which encoded the full-length coding sequence of MET without its 3′-UTR (Figure 6a). The gene discussed is MET; the disease is neoplasm.