APOB and Beta-thalassemia: In a study performed on minor beta thalassemia carriers in Sardinia, not only LDL (low density of lipoprotein) level of thalassemia patients was lower compared to the control group, but also they showed significant decrease of Apo A and Apo B. Indeed, some alterations in LDL and HDL protein content have been reported and the researchers have suggested that in minor beta thalassemia patients, myocardial infarction happens 10 years later in comparison to the control group [15].