CD8A and breast carcinoma: Our findings on CD8 positive lymphocyte infiltration associated with lack of lymph node involvement are consistent with those reported by Sheu et al., who showed similar results for breast cancer [18], Lee et al., who demonstrated a correlation between CD8+ TILs and negative lymph node status for gastric cancer [30], and Piersma et al., who showed similar results for early-stage cervical cancer [19].