Only 34.4% of WHO grade I meningiomas were PD-L1 mRNA high expressors (Fig. 3C) defined as cases with scores above the median for the entire cohort, 179.9, Table S4) whereas 71.8% of WHO grade II meningiomas were high expressors (p < 0.001) and 82.4% of WHO grade III meningiomas were high expressors (p < 0.001 (Fig. 3C). This evidence concerns the gene CD274 and meningioma.