EPHA5 and Familial prostate cancer: To explore the potential role of EphA5 in prostate carcinogenesis, we first analyzed its expression by real-time PCR in a panel of human nonmalignant (RWPE-1) and prostate cancer (LNCaP, LNCaP-LN3, PC-3, PC-3M-LN4, CWR22rv-1, and DU145) cell lines.