PVR and Miyoshi myopathy: To determine whether this molecular pathway might be involved in PVR/CD155 up-regulation in MM cells, SKO-007(J3) cells were treated with DETA-NO in the presence or absence of ODQ, a widely used specific inhibitor of soluble guanylate cyclase used to differentiate cGMP-mediated effects of NO from cGMP-independent effects [33,34].