In particular, as shown in Figure 3D, the presence of anti-CCL2 Ab significantly reduced the amount of episomal 2-long terminal repeat (2-LTR) DNA circles accumulated 7 days post-infection with respect to control Ab treatment [0.26 ± 0.14 (SE) fold vs. control Ab; p < 0.05; n = 3]. The gene discussed is CCL2; the disease is infection.