However, we did not obtain complete KS phenotype, so it is likely that cooperation with other KSHV proteins (e.g., vGPCR, LANA, vCyclin, vIL-6, K1) and/or noncoding transcripts (e.g., miR 17–92, miR K12-7), which are co-expressed in KS and relevant for vascular tumorigenesis, are required for full pathogenesis [48–52]. The gene discussed is KRT1; the disease is Kaposi's sarcoma.