IL6 and Lymphadenopathy: KSHV is also associated with KSHV inflammatory cytokine syndrome (KICS), a newly described clinical condition characterized by systemic illness, poor prognosis, elevated KSHV titers, increased levels of viral IL6 and IL10 comparable to those seen in KSHV–MCD but lacking the characteristic lymphadenopathy of KSHV–MCD [4,5], and KSHV-associated hemophagocytic syndrome (VAHS), an extremely rare syndrome reported in immunocompromised patients with MCD and markedly elevated levels of serum human IL6 [6].