Secondary amyloidosis has been associated with chronic inflammatory conditions such as rheumatoid arthritis [8] or multiple sclerosis [9].In addition, SAA is recognized as a potential biomarker for a variety of chronic diseases including diabetes, cardiovascular disease (CVD), different types of cancers, sickle-cell disease, traumatic tissue damage and infections [10–13]. Here, SAA1 is linked to AA amyloidosis.