Okamura and colleagues [14] found that the SUVs for 12 joints correlated with tender joint count (TJC) and that the SUVs for eight joints correlated with DAS28, DAS28-C-reactive protein (CRP), and TJC in patients with RA, suggesting a close relationship between SUVs for large joints and disease activity. This evidence concerns the gene CRP and rheumatoid arthritis.