GSTP1 and Familial prostate cancer: Individuals with homozygous genotypes of GSTP1 Ile/Ile were reported to have the lowest risk of prostate cancer (Kote-Jarai et al., 2001), and this genotype is found to be protective in rheumatoid arthritis (Mattey et al., 1999) and basal cell carcinoma (Ramachamdran et al., 2000).