Preventive oophorectomy was reported to be associated with an 80% reduction in the risk of ovarian, fallopian tube, or peritoneal cancer in BRCA1 or BRCA2 carriers and a 77% reduction in all-cause mortality [51], even if it has been observed that BRCA1/2-associated OC patients have a longer progression-free survival and overall survival compared with women with sporadic OC [52],[53]. Here, BRCA2 is linked to peritoneum cancer.