ALK and T-cell non-Hodgkin lymphoma: It is unclear why these ALK -ve cells do not undergo natural apoptosis as a result of the failed TCR gene recombination but of interest the 5 year overall survival for ALK –ve T cell lymphoma at 49%, whilst significantly lower than that of ALK + VE [70%] is significantly higher than the 32% reported other peripheral T cell malignancies [225].