The comparison of the CD4+/CD8+ ratio between the peripheral blood, the tumor tissues, and the dLN of the patients’ samples indicated that the ratio for the dLN (4.3 ± 0.45) was significantly higher than those for the peripheral blood (2.08 ± 0.19, P = 0.001) and the tumor tissues (0.33 ± 0.07, P<0.0001). This evidence concerns the gene CD8A and neoplasm.