USP22 expression is increased in laryngeal squamous cell carcinoma (Li et al. 2014), salivary adenoid cystic carcinoma (Dai et al. 2014), cervical cancer (Yang et al. 2014), salivary duct carcinoma (Piao et al. 2013), colorectal carcinoma (Liu et al. 2010), breast cancer (Zhang et al. 2011a), oral squamous cell carcinoma (Piao et al. 2012), and papillary carcinoma (Wang et al. 2013). This evidence concerns the gene USP22 and thyroid gland papillary carcinoma.