ROBO1 and colorectal carcinoma: Although, our in vitro data in one of the cell lines (SW480) were not consistent with what has been previously published [24], we have consistently shown in two CRC cell lines (SW480 and SW620) and by a complementary approach in another cell line HCT-116, that activation of Slit2/Robo1 signaling may exert oncogenic effects during the CRC development.