CXXC5 and acute myeloid leukemia: CXXC5 was knocked down by lentiviral vectors in three different AML cell lines; one vector with pyromycine selection was used for MV4-11 (759 genes upregulated and 744 genes downregulated at least 1.5 fold) and K562 cells (870 genes upregulated and 758 genes downregulated at least 1.5 fold) and another vector based on GFP sorting was used for knockdown in K562 (356 genes upregulated and 457genes downregulated at least 1.5 fold) and UT7 cells (1291 genes upregulated and 827 genes downregulated at least 1.5 fold).