We also report that the EZH2GOF DLBCL cells overexpress BBAP, (B-lymphoma and BAL-associated protein), an E3 ligase involved in monoubiquitination of histone H4K91 [15], a factor that was shown to be associated with chemoresistance previously [16-18]. This evidence concerns the gene DTX3L and diffuse large B-cell lymphoma.