Interestingly, serum level of gal-1 also correlates with lymph node metastasis of the patients, as shown in Table 1, the patients with lymph node metastasis displayed a significantly higher gal-1 level (56.61 ± 14.68 ng/ml) in blood circulation that those without lymph node metastasis (31.54 ± 8.32 ng/ml). This evidence concerns the gene LGALS1 and metastatic malignant neoplasm in the lymph nodes.