2010). Expression of CT453 was lower early in development, peaked at 24 h post infection, and increased more than 20-fold during development (Fig. S1C) (Belland et al. 2003). The confirmation that CT453 and CT775 represent actively expressed genes in C. trachomatis was obtained by detection of matching peptides in the proteome analysis of the bacteria (Saka et al. 2011). This evidence concerns the gene CT45A3 and infection.