Significant difference could be calculated for prevalence of factor-V-Leiden and hyperhomocysteinemia between AIVC and NoAIVC patients (prevalence of factor-V-Leiden, 16.4% vs. 4.8%; p = 0.001; prevalence of hyperhomocysteinemia, 12.1% vs. 3.0%; p < 0.0001; Tables 3 and 4). Here, F5 is linked to hyperhomocysteinemia.