Moreover, adoptive transfer experiments in which we subretinally injected thioglycollate-elicited WT-CFSE+-Mφs into WT or FasL-defective mice (FasLgld/gldmice), and Fas-defective CFSE+ Mφs (prepared from thioglycollate-elicited peritonitis of Faslpr/lpr mice) into WT mice, revealed that subretinal CFSE+F4/80+-Mφs were significantly greater in number 24 h after the injection when FAS or FASL function was impaired (Fig5I) and comparable to the phenotype observed in Cx3cr1GFP/GFP Mφs (Fig3). Here, FAS is linked to peritonitis.