Finally, to test whether CD14-dependent IL-6 induction does indeed participate in subretinal MP accumulation in vivo, we injected control IgG (Fig6I), an IL-6- (Fig6J) or CD14-neutralizing antibody into the vitreous of Cx3cr1GFP/GFP mice and induced subretinal inflammation with a laser injury (which also facilitates antibody penetration into the subretinal space). Here, CD14 is linked to inflammatory response.