AMD is presented in two major forms, the dry form which is associated with degeneration of retinal pigment epithelium (RPE), and the exudative or wet form which presents the formation of choroidal neovascularization (CNV) (Hua et al. 2012).The impairment of RPE cell function is an early and crucial event in the molecular pathways leading to clinically relevant AMD changes associated with increased production of vascular endothelial growth factor (VEGF) and CNV. The gene discussed is VEGFA; the disease is choroidal neovascularization.