While O‐Sed rats had higher mRNA level of Plin2, a gene involved in CLD formation, than L‐Sed rats, O‐EndEx rats had even greater mRNA levels of Plin2 and Plin3 compared with L‐Sed rats and O‐Sed rats (P < 0.05; Fig. 2B). Here, PLIN3 is linked to congenital secretory chloride diarrhea 1.