Although bacterial burdens in the spleens and livers of control and HOIL-1 KO mice were similar 1 and 3 days post-infection with 105 CFU, bacterial CFUs were elevated in HOIL-1 KO mice by 6 days post-infection, indicating that HOIL-1 KO mice were unable to control and clear the bacteria (Figure 1B). Here, RBCK1 is linked to infection.