TNF and listeriosis: To determine whether MHV68 latency rescued pro-inflammatory cytokine induction by HOIL-1 KO mice following Listeria infection, we quantitated cytokine transcripts in peritoneal cells from latently infected mice before (Figure 5C) and 3 hr after (Figure 5D) infection with Listeria. As predicted from the cytokine levels in the serum, MHV68 latency resulted in small but significant increases in Tnf, Il6 and Il12b transcripts prior to Listeria challenge (Figure 5C).