The data presented in Figures 3 A and B show that the percentage of OVA specific SIINFEKL binding CD8+ T-cells (p < 0.01) as well as the ability to induce TNFα and IFNγ are significantly suppressed (p < 0.001 and p < 0.01 respectively) in OVA primed GL261 bearing mice (white bars) compared to non-tumor bearing mice (black bars). The gene discussed is TNF; the disease is neoplasm.