IL1B and atherosclerosis: It has been previously demonstrated that LOX-1 expression can be modulated by many stimuli related to atherosclerosis, including proinflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-α) , angiotensin II and oxidized low density lipoprotein (OX-LDL) (16) .