Results from both statistical analyses indicated that SKP2 expression was positively correlated with H3K4me3 levels (Pearson correlation coefficient = 0.4693, P = 0.0044; χ2 test, P = 0.0006) in PCa (Figure 6B and Supplementary Table S2), when graded in intensity staining scores, respectively. This evidence concerns the gene SKP2 and posterior cortical atrophy.