Meanwhile, the staining assays revealed that miR-500–overexpressing tumours had increased percentages of Ki67-positive cells and decreased percentages of TUNEL-positive cells, whereas miR-500–silenced tumours had a lower Ki67 proliferation index and a higher percentage of TUNEL-positive apoptotic cells (Figure 3D and 3E). The gene discussed is MKI67; the disease is neoplasm.