Following our analysis of non-cancerous HEK 293T cells at which the regulation of Fyn expression by miR-125a-3p has been established [22], we confirmed that this regulation applies also in prostate cancer cell.In view of former evidence of miRNA's critical role in tumor invasion and metastasis [24] we focused on studying the potential involvement of miR-125a-3p in cellular pathways leading to motility and migration of cancer cells. The gene discussed is FYN; the disease is prostate carcinoma.