We then analyzed the prognostic value of EGFR in gliomas dichotomized according to high versus low expression level of EFEMP1 and also the prognostic value of EFEMP1 in the same set of gliomas dichotomized according to high versus low expression value of EGFR. A log-rank test showed a significant difference among the four groups of gliomas (P value = 0.010). This evidence concerns the gene EGFR and central nervous system cancer.