Interestingly, our data on exosomal protein profiles from treated Caco-2 showed an enrichment of upregulated proteins involved in tumor etiopathogenesis, including CRC (CD59, CRP, CTSD, HMMR, LY6K, TRIM22), and in cell cycle control (BRAF, CDC2, ERBB2). This evidence concerns the gene ERBB2 and colorectal carcinoma.