MALAT1 and lung adenocarcinoma: As mentioned previously, MALAT1 high expression was at first identified as a prognosis factor for metastasis and survival in patients with early stage lung adenocarcinomas [298], however, also in squamous cell lung cancer MALAT1 overexpression is associated with a poor prognosis, correlating with an increased cell growth and colony formation of NSCLC cells in vitro [300].