To determine whether oncogenic Kras was capable of inducing ATDC expression, we measured ATDC levels in both a mouse PDA cell line (derived from KrasG12D;Trp53R172H;p48-Cre mice [KPC mice]) and human (Capan2) pancreatic cancer cell lines expressing control or ATDC shRNA lentiviral vectors. This evidence concerns the gene KRAS and familial pancreatic carcinoma.