GSDMB and asthma: In the analysis with equal weights and defining functional variants more broadly, associations with GSDMB and ZPBP2, two genes at the 17q12–21 asthma locus, were significant in the combined (MetaSKAT-O: P=6.10 × 10−10, 16 variants and P=1.34 × 10−6, 7 variants, respectively; N=9,501) and Latino (MetaSKAT-O: P=1.02 × 10−6, 12 variants and P=1.73 × 10−6, 7 variants, respectively; N=3,912) samples after Bonferroni correction for 9,534 and 10,439 genes, respectively.