Chronic kidney disease (CKD) is accompanied by profound disturbances in calcium (Ca), phosphate (P), vitamin D (Vit D), and intact parathyroid hormone (iPTH) homeostasis that play a crucial role in the pathophysiology of renal bone disease.1 Renal osteodystrophy encompasses 3 distinct histological entities: high turnover, which includes osteitis fibrosa cystica and is associated with high iPTH levels; adynamic bone disease associated with low iPTH levels; and mixed.2 This evidence concerns the gene PTH and chronic kidney disease.