We next examined the effects of these molecules in a selection of solid tumor cell lines reported to rely on MCL-1 for survival, including the NSCLC cell lines H2110 and H23.24, 29 siRNA rescue experiments (Figures 5a and c) and BH3 profiling (Figure 5e) confirmed that these cell lines are dependent on MCL-1 for survival. Here, MCL1 is linked to non-small cell lung carcinoma.