These “helper” NK cells potently attract iDCs in a CCR5-dependent mechanism and induce high DC production of CXCR3 and CCR5 ligands (CXCL9, CXCL10 and CCL5), thereby facilitating the ensuing recruitment of type-1 effector CD8+ T (Teff) cells in the tumor microenvironment. This evidence concerns the gene CD8A and neoplasm.