IFT88 and Renal cyst: Most interesting with regard to the analysis of both Tg737 alleles and future analysis of ciliary function during development were the different phenotypes observed in these two Tg737 alleles: these included cystic kidneys in the hypomorphic orpk allele and a more severe phenotype involving motile monocilia at the node in the complete loss-of-function Tg737D2-3bGal allele.