GZMB and tuberculosis: Thus, we observed that in TB-IRIS patients receiving prednisone treatment for 2 wk, granzyme B secretion was decreased in vitro (n = 16; median, 233 pg/ml; IQR, 66–2312 pg/ml) compared with pretreatment responses (median, 1068; IQR, 6–6672; p = 0.03).