To explore differences between stimulated PBMC from patients with TB-IRIS as compared with non-IRIS patients that would account for the differentially increased IFN-γ release by TB-IRIS PBMC in response to hkH37Rv shown above, we investigated differential transcript abundance by microarray analysis of RNA from PBMC stimulated for 6 h with hkH37Rv. Here, IFNG is linked to tuberculosis.