There is substantial evidence that the Type-1 T lymphocytes (Th1) predominantly secreting interleukin 2 (IL-2) and interferon (IFN)-γ are pathogenic in the evolution of corneal disease, since the neutralization of IL-2 and IFN-γ results in the remission of HSK [36–38, 54]. Here, IL2 is linked to corneal disorder.