In view of the predicted increased incidence of T2DM in sub-Saharan Africa, a continent that is still grappling with malaria-imposed health challenges, coupled with a recent finding that diabetics are more prone to getting malaria [5], we sought to investigate whether uncomplicated malaria in adult could alter insulin resistance and beta cell function in diabetics receiving treatment at the Cape Coast Teaching Hospital (CCTH) compared with age-matched nondiabetic controls. The gene discussed is INS; the disease is diabetes mellitus.