Although stromal VCAN expression was associated with a poor prognosis in oral squamous cell carcinoma [70] and was associated with high rate of tumor recurrence and more advanced disease in non-small cell lung cancers [71], our data does not yet confirm a direct link between VCAN overexpression and many of the clinicopathological and prognostic features in ACC. This evidence concerns the gene VCAN and oral cavity squamous cell carcinoma.