To study functional roles of MYB and MYB-NFIB in ACC tumorigenesis, we generated expression vectors including full-length MYB with intact 5′ and 3′ UT (MYB wt); MYB with only 5′UT (MYB no 3′UTR), truncated MYB with a stop codon inserted at the most common translocation breakpoint in exon 15 (Trunc MYB), and MYB-NFIB fusion (MYB-NFIB) (Figure 6A). This evidence concerns the gene NFIB and adrenal cortex carcinoma.